Gene: ME1

Alternate names for this Gene: HUMNDME|MES

Gene Summary: This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Gene is located in Chromosome: 6

Location in Chromosome : 6q14.2

Description of this Gene: malic enzyme 1

Type of Gene: protein-coding