Gene: MICAL1

Alternate names for this Gene: MICAL|MICAL-1|NICAL

Gene Summary: This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: microtubule associated monooxygenase, calponin and LIM domain containing 1

Type of Gene: protein-coding

rs397771537 in MICAL1 gene and Body Height PMID 28552196 2017 Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

rs9487114 in MICAL1 gene and Major Depressive Disorder PMID 30219690 2019 GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.

rs9487114 in MICAL1 gene and Smoking PMID 30219690 2019 GWAS and systems biology analysis of depressive symptoms among smokers from the COPDGene cohort.