Gene: MIR1322

Alternate names for this Gene: MIRN1322|hsa-mir-1322

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 8

Location in Chromosome : 8p23.1

Description of this Gene: microRNA 1322

Type of Gene: ncRNA

Gene: PINX1

Alternate names for this Gene: Gno1|LPTL|LPTS|Pxr1

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8p23.1

Description of this Gene: PIN2 (TERF1) interacting telomerase inhibitor 1

Type of Gene: protein-coding

rs11776767 in MIR1322;PINX1 gene and Triglycerides measurement PMID 20686565 2010 Biological, clinical and population relevance of 95 loci for blood lipids.

PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.