Gene: MIR3655

Alternate names for this Gene: -

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.3

Description of this Gene: microRNA 3655

Type of Gene: ncRNA

Gene: NDUFA2

Alternate names for this Gene: B8|CD14|CIB8|MC1DN13

Gene Summary: The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.3

Description of this Gene: NADH:ubiquinone oxidoreductase subunit A2

Type of Gene: protein-coding

Gene: IK

Alternate names for this Gene: CSA2|RED|RER

Gene Summary: The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.3

Description of this Gene: IK cytokine

Type of Gene: protein-coding

Gene: TMCO6

Alternate names for this Gene: PRO1580

Gene Summary:

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.3

Description of this Gene: transmembrane and coiled-coil domains 6

Type of Gene: protein-coding

rs778591 in MIR3655;NDUFA2;IK;TMCO6 gene and Intelligence PMID 29942086 2018 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.