Gene: MMP24-AS1-EDEM2

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: MMP24OS

Alternate names for this Gene: MMP24-AS1

Gene Summary:

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.22

Description of this Gene: MMP24 opposite strand

Type of Gene: protein-coding

Gene: MMP24

Alternate names for this Gene: MMP-24|MMP25|MT-MMP 5|MT-MMP5|MT5-MMP|MT5MMP|MTMMP5

Gene Summary: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase). The gene has previously been referred to as MMP25 but has been renamed matrix metallopeptidase 24 (MMP24).

Gene is located in Chromosome: 20

Location in Chromosome : 20q11.22

Description of this Gene: matrix metallopeptidase 24

Type of Gene: protein-coding

rs2425025 in MMP24-AS1-EDEM2;MMP24OS;MMP24 gene and Suntan PMID 29739929 2018 Genome-wide association study in 176,678 Europeans reveals genetic loci for tanning response to sun exposure.