Gene: MORC3

Alternate names for this Gene: NXP2|ZCW5|ZCWCC3

Gene Summary: This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.12

Description of this Gene: MORC family CW-type zinc finger 3

Type of Gene: protein-coding

rs62229372 in MORC3 gene and Diastolic blood pressure PMID 30224653 2018 Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

rs62229372 in MORC3 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs4817795 in MORC3 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.