Gene: MPIG6B

Alternate names for this Gene: C6orf25|G6b|G6b-B|NG31|THAMY

Gene Summary: This gene is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. The protein encoded by this gene is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: megakaryocyte and platelet inhibitory receptor G6b

Type of Gene: protein-coding

Gene: LY6G6C

Alternate names for this Gene: C6orf24|G6c|NG24

Gene Summary: LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: BC036302.1, AY359119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375819.3/ ENSP00000364978.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: lymphocyte antigen 6 family member G6C

Type of Gene: protein-coding