Gene: MPO
Alternate names for this Gene: -
Gene Summary: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
Gene is located in Chromosome: 17
Location in Chromosome : 17q22
Description of this Gene: myeloperoxidase
Type of Gene: protein-coding