Gene: MPP3

Alternate names for this Gene: DLG3

Gene Summary: This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.31

Description of this Gene: membrane palmitoylated protein 3

Type of Gene: protein-coding

rs12950756 in MPP3 gene and Bone Density PMID 29304378 2018 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

rs8077889 in MPP3 gene and Triglycerides measurement PMID 24097068 2013 Discovery and refinement of loci associated with lipid levels.