Gene: MS4A5

Alternate names for this Gene: CD20-L2|CD20L2|TETM4

Gene Summary: This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Though this member is not expressed in hematopoietic cells specifically, it may be involved in signal transduction like many of its related family members. The gene encoding this protein is localized to 11q12, among a cluster of family members.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.2

Description of this Gene: membrane spanning 4-domains A5

Type of Gene: protein-coding

rs73481300 in MS4A5 gene and Memory, Short-Term PMID 30741946 2019 Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.

rs11230328 in MS4A5 gene and Prostate carcinoma PMID 27515689 2016 Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer.