Gene: MS4A7

Alternate names for this Gene: 4SPAN2|CD20L4|CFFM4|MS4A8

Gene Summary: This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.2

Description of this Gene: membrane spanning 4-domains A7

Type of Gene: protein-coding

Gene: MS4A14

Alternate names for this Gene: MS4A16|NYD-SP21

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.2

Description of this Gene: membrane spanning 4-domains A14

Type of Gene: protein-coding

rs950802 in MS4A7;MS4A14 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.