Gene: MSH5-SAPCD1

Alternate names for this Gene: MSH5-C6orf26

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring mutS homolog 5 (MSH5) and chromosome 6 open reading frame 26 (C6orf26) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: MSH5-SAPCD1 readthrough (NMD candidate)

Type of Gene: ncRNA

Gene: SAPCD1

Alternate names for this Gene: C6orf26|NG23

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: suppressor APC domain containing 1

Type of Gene: protein-coding

Gene: MSH5

Alternate names for this Gene: G7|MUTSH5|NG23|POF13

Gene Summary: This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: mutS homolog 5

Type of Gene: protein-coding