Gene: MTX1

Alternate names for this Gene: MTX|MTXN

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: metaxin 1

Type of Gene: protein-coding

Gene: THBS3

Alternate names for this Gene: TSP3

Gene Summary: The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants.

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: thrombospondin 3

Type of Gene: protein-coding

rs760077 in MTX1;THBS3 gene and Blood urea nitrogen measurement PMID 28270201 2017 Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.

rs760077 in MTX1;THBS3 gene and Glomerular Filtration Rate PMID 31451708 2019 Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program.

rs760077 in MTX1;THBS3 gene and Hematocrit procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs760077 in MTX1;THBS3 gene and Hemoglobin measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs760077 in MTX1;THBS3 gene and Red Blood Cell Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs760077 in MTX1;THBS3 gene and Stomach Carcinoma PMID 31383772 2020 Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations.

PMID 26098866 2015 Loss-of-function variants in ATM confer risk of gastric cancer.

rs760077 in MTX1;THBS3 gene and Uric acid measurement (procedure) PMID 31578528 2019 Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.