Gene: MYO7B

Alternate names for this Gene: -

Gene Summary: The protein encoded by this gene is found in brush border microvilli of epithelial cells in the intestines and kidneys. The encoded protein is involved in linking protocadherins to the actin cytoskeleton and is essential for proper microvilli function. This protein aids in the accumulation of intermicrovillar adhesion components such as harmonin and ANKS4B, and this accumulation is necessary for normal brush border action.

Gene is located in Chromosome: 2

Location in Chromosome : 2q14.3

Description of this Gene: myosin VIIB

Type of Gene: protein-coding

rs1019842 in MYO7B gene and Protein C antigen measurement PMID 20802025 2010 Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.

PMID 25376901 2014 Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study.

rs1019842 in MYO7B gene and Protein C measurement PMID 20802025 2010 Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.

PMID 25376901 2014 Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study.

rs4662750 in MYO7B gene and Renal Cell Carcinoma PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.