Gene: MYRF
Alternate names for this Gene: 11orf9|C11orf9|CUGS|MMERV|MRF|Ndt80|pqn-47
Gene Summary: This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 11
Location in Chromosome : 11q12.2
Description of this Gene: myelin regulatory factor
Type of Gene: protein-coding