Gene: NAA38

Alternate names for this Gene: LSMD1|MAK31|PFAAP2

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: N-alpha-acetyltransferase 38, NatC auxiliary subunit

Type of Gene: protein-coding

Gene: CHD3

Alternate names for this Gene: Mi-2a|Mi2-ALPHA|SNIBCPS|ZFH

Gene Summary: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.1

Description of this Gene: chromodomain helicase DNA binding protein 3

Type of Gene: protein-coding

rs377079849 in NAA38;CHD3 gene and Eosinophil count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs377079849 in NAA38;CHD3 gene and Granulocyte count PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs377079849 in NAA38;CHD3 gene and Neutrophil count (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs7503751 in NAA38;CHD3 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.