Gene: NAALADL2

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3q26.31

Description of this Gene: N-acetylated alpha-linked acidic dipeptidase like 2

Type of Gene: protein-coding

rs16824453 in NAALADL2 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs517875 in NAALADL2 gene and Endometriosis PMID 28333195 2017 Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.

rs4459914 in NAALADL2 gene and Impaired cognition PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.

rs13326866 in NAALADL2 gene and Ischemic stroke PMID 30796134 2019 Genome-wide association meta-analysis of functional outcome after ischemic stroke.

rs17531088 in NAALADL2 gene and Mucocutaneous Lymph Node Syndrome PMID 19132087 2009 Significant associations of 40 SNPs and six haplotypes, identifying 31 genes, were replicated in an independent cohort of 583 predominantly Caucasian KD families, with NAALADL2 (rs17531088, p(combined) = 1.13 x 10(-6)) and ZFHX3 (rs7199343, p(combined) = 2.37 x 10(-6)) most significantly associated.

rs73050171 in NAALADL2 gene and Proliferative diabetic retinopathy PMID 30487263 2019 Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

rs78943174 in NAALADL2 gene and Prostate carcinoma PMID 25939597 2015 In a multistage, case-only genome-wide association study of 12,518 prostate cancer cases, we identify two loci associated with Gleason score, a pathological measure of disease aggressiveness: rs35148638 at 5q14.3 (RASA1, P=6.49 × 10(-9)) and rs78943174 at 3q26.31 (NAALADL2, P=4.18 × 10(-8)).

rs16824453 in NAALADL2 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs6771725 in NAALADL2 gene and Venous Thromboembolism PMID 23509962 2013 A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis.