Gene: NCF1

Alternate names for this Gene: CGD1|NCF1A|NOXO2|SH3PXD1A|p47phox

Gene Summary: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Gene is located in Chromosome: 7

Location in Chromosome : 7q11.23

Description of this Gene: neutrophil cytosolic factor 1

Type of Gene: protein-coding

rs145360423 in NCF1 gene and GRANULOMATOUS DISEASE, CHRONIC, AUTOSOMAL RECESSIVE, CYTOCHROME b-POSITIVE, TYPE III PMID 24446915 2015 Clinical and molecular findings of chronic granulomatous disease in Oman: family studies.