Gene: NEK4

Alternate names for this Gene: NRK2|STK2|pp12301

Gene Summary: The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies.

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: NIMA related kinase 4

Type of Gene: protein-coding

Gene: SPCS1

Alternate names for this Gene: HSPC033|SPC1|SPC12|YJR010C-A

Gene Summary:

Gene is located in Chromosome: 3

Location in Chromosome : 3p21.1

Description of this Gene: signal peptidase complex subunit 1

Type of Gene: protein-coding

rs11235 in NEK4;SPCS1 gene and Intelligence PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

PMID 29942086 2018 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.