Gene: NET1

Alternate names for this Gene: ARHGEF8|NET1A

Gene Summary: This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene is located in Chromosome: 10

Location in Chromosome : 10p15.1

Description of this Gene: neuroepithelial cell transforming 1

Type of Gene: protein-coding