Gene: NKAIN4
Alternate names for this Gene: C20orf58|FAM77A|bA261N11.2
Gene Summary: NKAIN4 is a member of a family of mammalian proteins (see NKAIN1; MIM 612871) with similarity to Drosophila Nkain and interacts with the beta subunit of Na,K-ATPase (ATP1B1; MIM 182330) (Gorokhova et al., 2007 [PubMed 17606467]).[supplied by OMIM, Jun 2009]. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.280928.1, SRR3476690.390042.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END##
Gene is located in Chromosome: 20
Location in Chromosome : 20q13.33
Description of this Gene: sodium/potassium transporting ATPase interacting 4
Type of Gene: protein-coding
rs1406961 in
NKAIN4 gene and
Cardiovascular Diseases
PMID 21779381 2011 Among migraineurs with aura rs7698623 in MEPE (OR = 6.37; 95% CI 3.15-12.90; p = 2.7×10(-7)) and rs4975709 in IRX4 (OR = 5.06; 95% CI 2.66-9.62; p = 7.7×10(-7)) appeared to be associated with ischemic stroke, rs2143678 located close to MDF1 with major CVD (OR = 3.05; 95% CI 1.98-4.69; p = 4.3×10(-7)), and the intergenic rs1406961 with CVD death (OR = 12.33; 95% CI 4.62-32.87; p = 5.2×10(-7)).
rs1406961 in
NKAIN4 gene and
Pseudocholinesterase Measurement
PMID 21779381 2011 Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study.