Gene: NLGN3
Alternate names for this Gene: HNL3
Gene Summary: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Gene is located in Chromosome: X
Location in Chromosome : Xq13.1
Description of this Gene: neuroligin 3
Type of Gene: protein-coding
rs34927195 in
NLGN3 gene and
Dysmorphic features
PMID 23849776 2013 Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing.
PMID 15150161 2004 Disorder-associated mutations lead to functional inactivation of neuroligins.
PMID 24570023 2014 Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.
PMID 12669065 2003 Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
rs34927195 in
NLGN3 gene and
Overgrowth
PMID 23849776 2013 Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing.
PMID 12669065 2003 Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.
PMID 24570023 2014 Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.
PMID 15150161 2004 Disorder-associated mutations lead to functional inactivation of neuroligins.