Gene: NLRC3

Alternate names for this Gene: CLR16.2|NOD3

Gene Summary: This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 16

Location in Chromosome : 16p13.3

Description of this Gene: NLR family CARD domain containing 3

Type of Gene: protein-coding

Gene: LOC105371060

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