Gene: NOS1AP

Alternate names for this Gene: 6330408P19Rik|CAPON

Gene Summary: This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: nitric oxide synthase 1 adaptor protein

Type of Gene: protein-coding

Gene: LOC105371475

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

rs1415259 in NOS1AP;LOC105371475 gene and Electrocardiography PMID 20062061 2010 Genetic variation in SCN10A influences cardiac conduction.

rs1415259 in NOS1AP;LOC105371475 gene and QT interval feature (observable entity) PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 20062061 2010 Genetic variation in SCN10A influences cardiac conduction.

PMID 19305408 2009 Common variants at ten loci influence QT interval duration in the QTGEN Study.

PMID 24952745 2014 Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

rs10918796 in NOS1AP;LOC105371475 gene and White Blood Cell Count procedure PMID 21738479 2011 Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).