Gene: NPHP3-ACAD11

Alternate names for this Gene: NPHP3

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring NPHP3 (nephronophthisis 3, adolescent) and ACAD11 (acyl-CoA dehydrogenase family, member 11) genes on chromosome 3. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: NPHP3-ACAD11 readthrough (NMD candidate)

Type of Gene: ncRNA

Gene: ACAD11

Alternate names for this Gene: ACAD-11

Gene Summary: This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: acyl-CoA dehydrogenase family member 11

Type of Gene: protein-coding

Gene: UBA5

Alternate names for this Gene: DEE44|EIEE44|SCAR24|THIFP1|UBE1DC1

Gene Summary: This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1.

Gene is located in Chromosome: 3

Location in Chromosome : 3q22.1

Description of this Gene: ubiquitin like modifier activating enzyme 5

Type of Gene: protein-coding

rs16839481 in NPHP3-ACAD11;ACAD11;UBA5 gene and Iron binding capacity total measurement PMID 28334935 2017 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

rs16839481 in NPHP3-ACAD11;ACAD11;UBA5 gene and Total iron binding capacity function PMID 28334935 2017 Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?