Gene: NPPC

Alternate names for this Gene: CNP|CNP2

Gene Summary: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cardiac natriuretic peptides CNP-53, CNP-29 and CNP-22, which belong to the natriuretic family of peptides. The encoded peptides exhibit vasorelaxation activity in laboratory animals and elevated levels of CNP-22 have been observed in the plasma of chronic heart failure patients.

Gene is located in Chromosome: 2

Location in Chromosome : 2q37.1

Description of this Gene: natriuretic peptide C

Type of Gene: protein-coding

rs5268 in NPPC gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs3107179 in NPPC gene and Height PMID 21194676 2011 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.