Gene: NPSR1-AS1

Alternate names for this Gene: AAA1

Gene Summary: This gene is located within a region that has been associated with asthma susceptibility. The locus is considered non-protein-coding based on lack of protein homology and a lack of experimental support for an encoded protein. Three alternatively spliced transcript variants have been identified for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7p14.3

Description of this Gene: NPSR1 antisense RNA 1

Type of Gene: ncRNA

Gene: NPSR1

Alternate names for this Gene: ASRT2|GPR154|GPRA|NPSR|PGR14|VRR1

Gene Summary: This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 7

Location in Chromosome : 7p14.3

Description of this Gene: neuropeptide S receptor 1

Type of Gene: protein-coding

rs325465 in NPSR1-AS1;NPSR1 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs323907 in NPSR1-AS1;NPSR1 gene and Thyroglobulin antibody measurement PMID 29678681 2019 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians.