Gene: NR1H4
Alternate names for this Gene: BAR|FXR|HRR-1|HRR1|PFIC5|RIP14
Gene Summary: This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene is located in Chromosome: 12
Location in Chromosome : 12q23.1
Description of this Gene: nuclear receptor subfamily 1 group H member 4
Type of Gene: protein-coding