Gene: NRTN

Alternate names for this Gene: NTN

Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.3

Description of this Gene: neurturin

Type of Gene: protein-coding