Gene: NTF3

Alternate names for this Gene: HDNF|NGF-2|NGF2|NT-3|NT3

Gene Summary: The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.31

Description of this Gene: neurotrophin 3

Type of Gene: protein-coding

rs7138947 in NTF3 gene and Sleep Initiation and Maintenance Disorders PMID 29520036 2018 Genome-wide analysis of insomnia disorder.