Gene: NTRK1

Alternate names for this Gene: MTC|TRK|TRK1|TRKA|Trk-A|p140-TrkA

Gene Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.1

Description of this Gene: neurotrophic receptor tyrosine kinase 1

Type of Gene: protein-coding

Gene: INSRR

Alternate names for this Gene: IRR

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.1

Description of this Gene: insulin receptor related receptor

Type of Gene: protein-coding