Gene: NUF2

Alternate names for this Gene: CDCA1|CT106|NUF2R

Gene Summary: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: NUF2 component of NDC80 kinetochore complex

Type of Gene: protein-coding