Gene: OGA

Alternate names for this Gene: MEA5|MGEA5|NCOAT

Gene Summary: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 10

Location in Chromosome : 10q24.32

Description of this Gene: O-GlcNAcase

Type of Gene: protein-coding

rs3740422 in OGA gene and Intelligence PMID 29942086 2018 Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.