Gene: OR5B12

Alternate names for this Gene: OR11-241|OR5B12P|OR5B16|OST743

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Gene is located in Chromosome: 11

Location in Chromosome : 11q12.1

Description of this Gene: olfactory receptor family 5 subfamily B member 12

Type of Gene: protein-coding

rs11229457 in OR5B12 gene and Diastolic blood pressure PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs11229457 in OR5B12 gene and Hypertensive disease PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs11229457 in OR5B12 gene and Systolic Pressure PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.