Gene: OSGIN1

Alternate names for this Gene: BDGI|OKL38

Gene Summary: This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product.

Gene is located in Chromosome: 16

Location in Chromosome : 16q23.3

Description of this Gene: oxidative stress induced growth inhibitor 1

Type of Gene: protein-coding