Gene: OTOGL

Alternate names for this Gene: C12orf64|DFNB84B

Gene Summary: The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness.

Gene is located in Chromosome: 12

Location in Chromosome : 12q21.31

Description of this Gene: otogelin like

Type of Gene: protein-coding

rs1551122 in OTOGL gene and Chronic Kidney Diseases PMID 29885931 2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

rs1551122 in OTOGL gene and Kidney Failure, Chronic PMID 29885931 2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.