Gene: PABPC1L

Alternate names for this Gene: C20orf119|EPAB|PABPC1L1|dJ1069P2.3

Gene Summary: This gene belongs to the polyadenylate-binding protein type-1 family of proteins. Members of this family bind to the polyA tails of mRNAs to regulate mRNA stability and translation. The mouse ortholog of this gene is required for female fertility. In human, expression of a functional protein is regulated by alternative splicing. The protein-coding splice variant for this gene is abundantly expressed in human oocytes, while a noncoding splice variant subject to nonsense-mediated decay is the predominant splice variant expressed in somatic tissues.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.12

Description of this Gene: poly(A) binding protein cytoplasmic 1 like

Type of Gene: protein-coding

Gene: YWHAB

Alternate names for this Gene: GW128|HEL-S-1|HS1|KCIP-1|YWHAA

Gene Summary: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.12

Description of this Gene: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

Type of Gene: protein-coding