Gene: PABPC1L

Alternate names for this Gene: C20orf119|EPAB|PABPC1L1|dJ1069P2.3

Gene Summary: This gene belongs to the polyadenylate-binding protein type-1 family of proteins. Members of this family bind to the polyA tails of mRNAs to regulate mRNA stability and translation. The mouse ortholog of this gene is required for female fertility. In human, expression of a functional protein is regulated by alternative splicing. The protein-coding splice variant for this gene is abundantly expressed in human oocytes, while a noncoding splice variant subject to nonsense-mediated decay is the predominant splice variant expressed in somatic tissues.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.12

Description of this Gene: poly(A) binding protein cytoplasmic 1 like

Type of Gene: protein-coding

rs2072727 in PABPC1L gene and Duration of sleep PMID 30846698 2019 Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates.