Gene: PAQR6

Alternate names for this Gene: PRdelta

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: progestin and adipoQ receptor family member 6

Type of Gene: protein-coding

Gene: PMF1-BGLAP

Alternate names for this Gene: PMF-1|PMF1

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence.

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: PMF1-BGLAP readthrough

Type of Gene: protein-coding

Gene: BGLAP

Alternate names for this Gene: BGP|OC|OCN

Gene Summary: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: bone gamma-carboxyglutamate protein

Type of Gene: protein-coding

rs759330 in PAQR6;PMF1-BGLAP;BGLAP gene and NEPHROLITHIASIS, CALCIUM OXALATE PMID 24886237 2014 A whole genome SNP genotyping by DNA microarray and candidate gene association study for kidney stone disease.