Gene: PCBP3

Alternate names for this Gene: ALPHA-CP3|PCBP3-OT1|PCBP3OT

Gene Summary: This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. The protein encoded by this gene lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 21

Location in Chromosome : 21q22.3

Description of this Gene: poly(rC) binding protein 3

Type of Gene: protein-coding

Gene: PCBP3-AS1

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rs2150453 in PCBP3;PCBP3-AS1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.