Gene: PCDH18

Alternate names for this Gene: PCDH68L

Gene Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.

Gene is located in Chromosome: 4

Location in Chromosome : 4q28.3

Description of this Gene: protocadherin 18

Type of Gene: protein-coding

rs9330353 in PCDH18 gene and Cardiovascular Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs9330353 in PCDH18 gene and Systolic Pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.