Gene: PCOLCE

Alternate names for this Gene: PCPE|PCPE-1|PCPE1

Gene Summary: Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: procollagen C-endopeptidase enhancer

Type of Gene: protein-coding

Gene: FBXO24

Alternate names for this Gene: FBX24

Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: F-box protein 24

Type of Gene: protein-coding

Gene: PCOLCE-AS1

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 7

Location in Chromosome : 7q22.1

Description of this Gene: PCOLCE antisense RNA 1

Type of Gene: ncRNA