Gene: PDCD11

Alternate names for this Gene: ALG-4|ALG4|NFBP|RRP5

Gene Summary: PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).[supplied by OMIM, Oct 2008]. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.69102.1, SRR1803613.113397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369797.8/ ENSP00000358812.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

Gene is located in Chromosome: 10

Location in Chromosome : 10q24.33

Description of this Gene: programmed cell death 11

Type of Gene: protein-coding

rs11191686 in PDCD11 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.