Gene: PDE11A
Alternate names for this Gene: PPNAD2
Gene Summary: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 2
Location in Chromosome : 2q31.2
Description of this Gene: phosphodiesterase 11A
Type of Gene: protein-coding
Gene: PDE11A-AS1
Alternate names for this Gene: -
Gene Summary:
Gene is located in Chromosome: 2
Location in Chromosome : 2q31.2
Description of this Gene: PDE11A antisense RNA 1
Type of Gene: ncRNA