Gene: PDE1A
Alternate names for this Gene: CAM-PDE 1A|CAM-PDE-1A|HCAM-1|HCAM1|HSPDE1A
Gene Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].
Gene is located in Chromosome: 2
Location in Chromosome : 2q32.1
Description of this Gene: phosphodiesterase 1A
Type of Gene: protein-coding