Gene: PDE4C

Alternate names for this Gene: DPDE1|PDE21

Gene Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.11

Description of this Gene: phosphodiesterase 4C

Type of Gene: protein-coding

rs4808762 in PDE4C gene and Uric acid measurement (procedure) PMID 31578528 2019 Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.