Gene: PDXDC1
Alternate names for this Gene: LP8165
Gene Summary:
Gene is located in Chromosome: 16
Location in Chromosome : 16p13.11
Description of this Gene: pyridoxal dependent decarboxylase domain containing 1
Type of Gene: protein-coding
Gene: NTAN1
Alternate names for this Gene: PNAA|PNAD
Gene Summary: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene is located in Chromosome: 16
Location in Chromosome : 16p13.11
Description of this Gene: N-terminal asparagine amidase
Type of Gene: protein-coding