Gene: PECAM1

Alternate names for this Gene: CD31|CD31/EndoCAM|GPIIA'|PECA1|PECAM-1|endoCAM

Gene Summary: The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Gene is located in Chromosome: 17

Location in Chromosome : 17q23.3

Description of this Gene: platelet and endothelial cell adhesion molecule 1

Type of Gene: protein-coding

rs9892152 in PECAM1 gene and Coronary Artery Disease PMID 29212778 2018 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.

rs6504218 in PECAM1 gene and Coronary heart disease PMID 21378988 2011 A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.

rs7225219 in PECAM1 gene and Systolic Pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.