Gene: PF4

Alternate names for this Gene: CXCL4|PF-4|SCYB4

Gene Summary: This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.

Gene is located in Chromosome: 4

Location in Chromosome : 4q13.3

Description of this Gene: platelet factor 4

Type of Gene: protein-coding