Gene: PFN2

Alternate names for this Gene: D3S1319E|PFL

Gene Summary: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.

Gene is located in Chromosome: 3

Location in Chromosome : 3q25.1

Description of this Gene: profilin 2

Type of Gene: protein-coding

rs16862394 in PFN2 gene and Respiratory Function Tests PMID 22837378 2012 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.